C-Peptide 2, rat is primarily used in research settings to study insulin secretion and beta-cell function in rodent models. It serves as a reliable marker for endogenous insulin production, allowing researchers to assess pancreatic islet activity without interference from exogenous insulin. Due to its stability in circulation, it is often measured in diabetes studies to evaluate disease progression, insulin resistance, and the effectiveness of therapeutic interventions. It is also used in metabolic research to differentiate between type 1 and type 2 diabetes in animal models, based on residual beta-cell function. Additionally, C-Peptide 2, rat supports investigations into islet transplantation and regeneration, providing insight into functional beta-cell mass after treatment.