N-Cbz-(3-hydroxymethyl)piperidine
97%
science Other reagents with same CAS 39945-51-2
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description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the piperidine ring is a structural component. The Cbz protection on the nitrogen and the free hydroxymethyl group allow for selective functionalization, enabling controlled chemical transformations in multi-step syntheses. Commonly employed in the preparation of central nervous system agents, including analgesics and neuroactive compounds. The hydroxyl group can be further modified through esterification or ether formation, while the Cbz group can be removed under mild conditions to liberate the amine for subsequent reactions. Valued in medicinal chemistry for its versatility and compatibility with various reaction conditions.
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