Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its structure supports the creation of compounds with enhanced metabolic stability and binding affinity. Commonly employed in the manufacture of fungicides and herbicides due to the electron-withdrawing properties of the trifluoromethyl group, which improves lipophilicity and environmental persistence. Also utilized in medicinal chemistry for constructing pyrimidine-based scaffolds in drug discovery programs targeting kinase inhibitors and central nervous system agents.