7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
98%
Reagent
Code: #205918
CAS Number
199327-61-2
blur_circular Chemical Specifications
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Molecular Information
Weight
319.36 g/mol
Formula
C₁₆H₂₁N₃O₄
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Registry Numbers
MDL Number
MFCD12760130
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Storage & Handling
Storage
2~8℃
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in anticancer drug development. Shows potential in targeting epidermal growth factor receptor (EGFR) pathways, making it valuable in research for lung, breast, and other solid tumor therapies. Its structure supports enhanced binding affinity and selectivity for mutant forms of EGFR, improving efficacy in resistant cancer strains. Also employed in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties of quinazoline-based drugs.
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