6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
98%
Reagent
Code: #167282
CAS Number
1256577-71-5
blur_circular Chemical Specifications
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Molecular Information
Weight
454.56 g/mol
Formula
C₂₈H₃₀N₄O₂
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9, which plays a key role in transcription regulation. It shows promise in oncology for targeting cancer cells by disrupting the transcription of survival genes, leading to apoptosis in tumor cells. Its structure allows for strong binding affinity and improved cellular permeability, making it a valuable scaffold in developing anticancer agents. Also investigated for antiviral applications due to its effect on transcriptional control in infected cells.
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