tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate

97%

Reagent Code: #128213
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CAS Number 617714-22-4

science Other reagents with same CAS 617714-22-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 225.28 g/mol
Formula C₁₂H₁₉NO₃
badge Registry Numbers
MDL Number MFCD17016701
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,220.00
inventory 250mg
10-20 days ฿9,300.00
inventory 500mg
10-20 days ฿16,070.00

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tert-Butyl 5-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
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Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the keton

Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of bioactive molecules with neurological activity. Its rigid bicyclic structure makes it valuable in medicinal chemistry for mimicking peptide conformations and enhancing metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor ligands where structural constraint improves selectivity and potency. Also utilized in the design of enzyme inhibitors due to the presence of the ketone functional group, which can act as a hydrogen bond acceptor or be further modified. Its protected amine (as Boc derivative) allows for selective deprotection and coupling in multi-step synthetic routes.

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