SYM 2081
science Other reagents with same CAS 31137-74-3
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Used primarily in neuroscience research, this compound acts as a selective agonist for kainate receptors, particularly targeting GluK1 (formerly known as GluR5) subtypes. It is utilized to study excitatory neurotransmission and synaptic plasticity in the central nervous system. Due to its ability to induce rapid and reversible activation of kainate receptors, it helps investigate receptor desensitization and ion channel kinetics. It is also employed in experimental models to probe the role of kainate receptors in pain pathways, epilepsy, and neurodegenerative conditions. Its selectivity makes it a valuable tool for distinguishing kainate receptor activity from other glutamate receptor subtypes like AMPA or NMDA.
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