Deschloroclozapine is primarily utilized in research settings, particularly in the field of neuroscience and pharmacology. It serves as a key compound in the study of receptor activity and signaling pathways, often acting as a control or reference substance in experiments involving clozapine derivatives. Its application is significant in understanding the pharmacological effects and mechanisms of action of related compounds, aiding in the development of new therapeutic agents for psychiatric and neurological disorders. Additionally, it is employed in the design and testing of chemogenetic tools, such as Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), to study neural circuits and brain function with high precision.