2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
97%
science Other reagents with same CAS 1013916-37-4
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description Product Description
Used as a key intermediate in the synthesis of cyclin-dependent kinase (CDK) inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to CDK enzymes, making it valuable in targeted cancer therapies. It has been studied in the context of inhibiting CDK2 and CDK4, which play critical roles in cell cycle regulation. Due to its ability to cross cell membranes and exhibit good metabolic stability, it is favored in medicinal chemistry for optimizing drug candidates aimed at treating solid tumors and hematological malignancies.
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