Used extensively in bioconjugation and crosslinking applications, particularly in the modification of proteins, peptides, and other biomolecules. It serves as a spacer or linker, enabling the attachment of molecules while maintaining their biological activity. Commonly employed in the development of antibody-drug conjugates (ADCs), where it connects cytotoxic drugs to antibodies, enhancing targeted drug delivery. Also utilized in surface modification of nanoparticles and biomaterials to improve biocompatibility and functionality. Its water-soluble nature and stability make it suitable for various biomedical and research applications, including diagnostics and therapeutic formulations.