(-)-Cedrusin is a chiral neolignan compound isolated from various medicinal plants, such as those in the Zanthoxylum genus. It is primarily used in biochemical and pharmacological research due to its potent anti-inflammatory effects, mediated by inhibition of NF-κB signaling pathways. Studies have also highlighted its antioxidant, antimicrobial, and potential cytotoxic activities against cancer cell lines. This compound serves as a valuable intermediate in natural product synthesis and drug discovery efforts targeting inflammatory diseases and oxidative stress-related conditions.