Fumagillin is primarily used in the field of aquaculture and beekeeping to control and treat microsporidian infections. In aquaculture, it is effective against parasites like Heterosporis and Loma species, which can infect fish and impact their health and growth. For beekeeping, fumagillin is widely employed to treat nosema disease, caused by the microsporidian parasite Nosema apis or Nosema ceranae, which affects the digestive systems of honeybees and can lead to colony collapse. Its application helps maintain healthy bee populations, which are crucial for pollination and agricultural productivity. Additionally, fumagillin has been explored in medical research for its potential anti-angiogenic properties, particularly in cancer studies, where it may inhibit the growth of blood vessels that supply tumors. However, its use in human medicine is limited due to toxicity concerns.