Fumonisin B1 is primarily associated with contamination in agricultural products, especially corn and corn-based foods. It is a mycotoxin produced by fungi of the *Fusarium* genus, and its presence poses significant health risks rather than beneficial applications. In agriculture and food safety, Fumonisin B1 is monitored closely because it can cause diseases in animals, such as equine leukoencephalomalacia in horses and porcine pulmonary edema in pigs. It is also linked to liver and kidney toxicity in humans and has been classified as a possible human carcinogen by health organizations. Due to these dangers, its main "application" lies in toxicological research and regulatory monitoring to ensure food and feed safety. Testing for Fumonisin B1 is standard in grain quality control to prevent contamination of the food supply chain.