Sodium pentafluoropropionate is primarily used in the field of organic synthesis as a reagent or intermediate. Its application is significant in the development of fluorinated compounds, which are often utilized in pharmaceuticals, agrochemicals, and specialty materials. The compound's fluorine atoms contribute to enhancing the stability, bioavailability, and metabolic resistance of the final products. In pharmaceutical research, it serves as a building block for creating molecules with potential therapeutic properties, particularly in the design of drugs targeting specific enzymes or receptors. Additionally, it finds use in the production of surfactants and coatings, where its fluorinated structure imparts unique properties like water and oil repellency, as well as chemical resistance.