4-(Trifluoromethyl)benzylsulfonyl chloride

≥98%

Reagent Code: #241101
fingerprint
CAS Number 163295-75-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 258.65 g/mol
Formula C₈H₆ClF₃O₂S
badge Registry Numbers
MDL Number MFCD01631932
thermostat Physical Properties
Melting Point 103-107 °C
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its sulfonyl chloride group readily reacts with nucleophiles such as amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester derivatives. These functional groups are common in bioactive molecules, including antidiabetic, antiviral, and anti-inflammatory agents. The electron-withdrawing trifluoromethyl group enhances metabolic stability and lipophilicity, which improves cell membrane permeability in drug candidates. It is also employed in the development of herbicides and insecticides due to the stability and reactivity profile imparted by the trifluoromethylbenzyl scaffold. Commonly used in medicinal chemistry for late-stage functionalization and library synthesis in drug discovery programs.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿2,150.00
inventory 5g
10-20 days ฿8,750.00
inventory 25g
10-20 days ฿43,100.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB