4-Chloro-2,3-difluorobenzoic acid
97%
Reagent
Code: #160135
CAS Number
150444-94-3
blur_circular Chemical Specifications
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Molecular Information
Weight
192.55 g/mol
Formula
C₇H₃ClF₂O₂
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Registry Numbers
MDL Number
MFCD07368122
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Physical Properties
Boiling Point
280.7°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors. Its structure supports enhanced metabolic stability and binding affinity in drug molecules. Also employed in agrochemicals to create herbicides and fungicides, where the halogen pattern improves bioavailability and target specificity. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its electron-withdrawing properties and ability to influence molecular conformation.
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