3,4,5,6-Tetrafluorobenzene-1,2-diol is primarily utilized in the synthesis of complex organic compounds, particularly in the pharmaceutical and agrochemical industries. Its fluorinated structure makes it a valuable intermediate for developing molecules with enhanced biological activity and stability.

In pharmaceuticals, it serves as a building block for creating drugs with improved metabolic resistance and bioavailability, often targeting specific enzymes or receptors. In agrochemicals, it is used to design pesticides and herbicides with higher efficacy and lower environmental impact.

Additionally, its unique chemical properties make it suitable for use in materials science, where it can be incorporated into polymers or coatings to impart specific characteristics like water repellency or chemical resistance. Its versatility and reactivity make it a key component in advanced chemical research and industrial applications.