Methyl 2-((Tert-Butyldimethylsilyl)Oxy)Acetate
97%
Reagent
Code: #212636
CAS Number
146351-72-6
blur_circular Chemical Specifications
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Molecular Information
Weight
204.34 g/mol
Formula
C₉H₂₀O₃Si
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a protected form of methoxyacetic acid in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The tert-butyldimethylsilyl (TBS) group acts as a protecting group for the hydroxyl functionality, allowing selective reactions at other sites in the molecule. This compound is valuable in multi-step syntheses where sensitive functional groups must be masked temporarily. It is commonly employed in the preparation of complex molecules such as natural products and active pharmaceutical ingredients (APIs), where controlled deprotection under mild conditions is required. Its stability under a variety of reaction conditions makes it ideal for use in acidic or basic environments, except in the presence of fluoride ions, which readily remove the TBS group.
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