ETHYL 1-BROMOCYCLOBUTANECARBOXYLATE
96%
Reagent
Code: #182213
CAS Number
35120-18-4
blur_circular Chemical Specifications
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Molecular Information
Weight
207.07 g/mol
Formula
C₇H₁₁BrO₂
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Registry Numbers
MDL Number
MFCD00001322
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Physical Properties
Boiling Point
85-88°C 12mm Hg (Lit.)
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Storage & Handling
Storage
2~8°C, sealed
description Product Description
Used as a key intermediate in organic synthesis, particularly in pharmaceutical and agrochemical manufacturing. Its bromine and ester functionalities allow for selective transformations—bromine serves as a handle for cross-coupling reactions (e.g., Suzuki or Negishi couplings), while the ester can be hydrolyzed to carboxylic acids or reduced to alcohols. Commonly employed in ring-expansion reactions and the construction of strained cyclobutane-containing molecules, which are increasingly important in drug design for conformational restriction. Also utilized in the synthesis of bioactive compounds where the cyclobutane motif enhances metabolic stability and target selectivity.
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