Used as a key building block in medicinal chemistry, particularly in the synthesis of bioisosteres for phenyl and other aromatic rings. Its rigid bicyclic structure helps improve metabolic stability, membrane permeability, and binding selectivity in drug candidates. Commonly employed in the development of CNS-active compounds and agrochemicals due to its favorable physicochemical properties. Also utilized in fragment-based drug discovery to introduce three-dimensionally constrained motifs into lead molecules.