Sulfatase from Helix pomatia is widely used in biochemical research and diagnostic applications. It plays a crucial role in the hydrolysis of sulfate esters, making it valuable for studying sulfated compounds in biological samples. In clinical diagnostics, it is employed to analyze and detect sulfated metabolites in urine and other bodily fluids, aiding in the diagnosis of metabolic disorders. Additionally, it is utilized in the preparation of desulfated products for further analysis in pharmaceutical and biochemical studies. Its ability to cleave sulfate groups also makes it useful in the modification of glycosaminoglycans and other sulfated biomolecules, facilitating research in glycobiology and enzymology.