Topotecan
10mM in DMSO
Reagent
Code: #128323
CAS Number
123948-87-8
science Other reagents with same CAS 123948-87-8
blur_circular Chemical Specifications
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Molecular Information
Weight
421.45 (nhydrous free base basis) g/mol
Formula
C₂₃H₂₃N₃O₅·xHCl·yH₂O
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Registry Numbers
MDL Number
MFCD00870670
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Storage & Handling
Storage
-20°C, Sealed
description Product Description
Used in chemotherapy to treat cancers such as ovarian cancer, small cell lung cancer, and cervical cancer. Works by inhibiting topoisomerase I, an enzyme involved in DNA replication, leading to cancer cell death. Administered intravenously, it is often used when other treatments have failed. Also being studied in combination with other anticancer drugs to improve effectiveness.
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