(8S,9R,10S,11S,13S,14S,16R,17R)-9-Chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
98%
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Widely used for its potent anti-inflammatory and immunosuppressive properties, this compound is primarily applied in the treatment of autoimmune diseases such as rheumatoid arthritis, lupus, and multiple sclerosis. It helps reduce inflammation in respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD) when administered via inhalation or systemic routes. In dermatology, it is formulated into creams and ointments to manage eczema, psoriasis, and allergic skin reactions due to its ability to constrict blood vessels and suppress immune activity in the skin. It is also used in ophthalmology for treating inflammatory eye conditions such as uveitis and allergic conjunctivitis. Additionally, it plays a role in managing severe allergic reactions and certain types of cancer, particularly lymphomas and leukemias, by inducing apoptosis in abnormal immune cells. Due to its strong biological activity, dosage and duration of use are carefully controlled to minimize side effects like adrenal suppression, bone loss, and increased infection risk.
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