Pimethixene maleate is primarily used as an antihistamine with anticholinergic properties. It is commonly prescribed to alleviate symptoms associated with allergic reactions, such as itching, sneezing, and runny nose. Additionally, it is effective in managing certain types of dermatitis and other skin conditions caused by allergic responses. Due to its sedative effects, it is sometimes used to aid in the treatment of insomnia or anxiety in patients who also require antihistamine therapy. It is also utilized in some cases to reduce symptoms of motion sickness. The compound works by blocking histamine receptors and inhibiting the action of acetylcholine, providing relief from various allergic and related conditions. Use under medical supervision due to potential side effects like drowsiness, dry mouth, and dizziness.