(1R,1'R,2S,2'S)-1,1'-(propane-1,3-diyl)bis(2-((2,6-diisopropylphenyl)carbamoyl)pyrrolidine 1-oxide)
99%
Reagent
Code: #229564
Alias
NO-Feng-PDIPPPR; NO-Feng-PDiPPr
CAS Number
945564-85-2
blur_circular Chemical Specifications
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Molecular Information
Weight
620.88 g/mol
Formula
C₃₇H₅₆N₄O₄
thermostat
Physical Properties
Melting Point
154-159 °C
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Storage & Handling
Storage
-20°C, Sealed
description Product Description
Used as a chiral organocatalyst in asymmetric synthesis, particularly in enantioselective oxidation and C–C bond-forming reactions. Its sterically hindered structure enhances selectivity, making it effective in promoting high enantiomeric excess in transformations such as aldol reactions and Michael additions. The N-oxide groups participate in hydrogen bonding, activating substrates through dual activation mechanisms. Commonly employed in pharmaceutical synthesis where precise stereochemistry is critical. Soluble in common organic solvents, it facilitates homogeneous reaction conditions and is often recovered and reused without significant loss of activity.
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