Used in organic synthesis as a chiral auxiliary or ligand in asymmetric catalysis, enabling the formation of enantiomerically enriched compounds. Its rigid oxazole core and naphthyridine moiety make it suitable for coordination with metal centers, enhancing stereoselectivity in reactions such as hydrogenations and C–C bond formations. Also investigated for potential applications in fluorescent probes due to the extended aromatic system, showing promise in sensing metal ions or biomolecules in solution. Additionally, derivatives of this scaffold appear in medicinal chemistry research for their biological activity, particularly in antimicrobial and antitumor studies.