tert-ButylN-[(1S,3R)-3-aminocyclopentyl]carbamate
98%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of protease inhibitors and antiviral agents. Its chiral cyclopentyl backbone with protected amine functionality allows for selective coupling reactions in multi-step drug synthesis. Commonly employed in the preparation of hepatitis C virus (HCV) NS3/4A protease inhibitors due to its ability to mimic peptide motifs and enhance metabolic stability. The tert-butoxycarbonyl (Boc) protection enables controlled deprotection under mild acidic conditions, making it suitable for solid-phase and solution-phase peptide-like assembly. Also utilized in the production of small molecule therapeutics targeting central nervous system disorders, where structural rigidity improves blood-brain barrier penetration.
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