(S)-1-Mesitylethanamine is primarily utilized in the field of asymmetric synthesis, where it serves as a chiral building block or ligand. Its sterically hindered structure makes it valuable in the development of catalysts for enantioselective reactions, particularly in the synthesis of pharmaceuticals and fine chemicals. The compound is often employed in the preparation of chiral amines, which are crucial intermediates in the production of various bioactive molecules. Additionally, it finds application in organic chemistry research for studying stereochemical outcomes and optimizing reaction conditions to achieve high enantiomeric purity. Its unique properties also make it suitable for use in the development of novel materials with specific chiral characteristics.