(E)-2'-Hydroxychalcone is widely studied for its potential biological and pharmacological applications. It exhibits significant antioxidant properties, making it a candidate for use in combating oxidative stress-related diseases. Research has shown its ability to inhibit the formation of free radicals, which can contribute to cellular damage and aging. Additionally, it has been explored for its anti-inflammatory effects, potentially offering therapeutic benefits in conditions like arthritis or other inflammatory disorders.

In the field of cancer research, (E)-2'-Hydroxychalcone has demonstrated promising anticancer activity by inducing apoptosis (programmed cell death) in certain cancer cell lines. Its ability to interfere with cancer cell proliferation makes it a subject of interest for developing novel chemotherapeutic agents.

Moreover, this compound has been investigated for its neuroprotective properties, suggesting potential applications in neurodegenerative diseases such as Alzheimer's or Parkinson's. Its ability to modulate signaling pathways and protect neurons from damage highlights its therapeutic potential in neurology.

In cosmetic and skincare formulations, (E)-2'-Hydroxychalcone is valued for its antioxidant and anti-aging properties, helping to protect the skin from environmental stressors and reduce signs of aging. Overall, its diverse biological activities make it a compound of interest across multiple scientific and industrial fields.