(2-Hydroxypropyl)-β-cyclodextrin
97%
Reagent
Code: #78833
Alias
Related CAS: 94035-02-6, 2-Hydroxypropyl-β-cyclodextrin ; Hydroxypropyl-β-cyclodextrin, Hydroxypropyl-beta-cyclodextrin
CAS Number
128446-35-5
science Other reagents with same CAS 128446-35-5
blur_circular Chemical Specifications
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Molecular Information
Weight
1541.54 g/mol
Formula
C₆₃H₁₁₂O₄₂
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Registry Numbers
EC Number
420-920-1
MDL Number
MFCD00069372
thermostat
Physical Properties
Melting Point
305 °C
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Storage & Handling
Storage
room temperature
description Product Description
(2-Hydroxypropyl)-β-cyclodextrin is widely used in the pharmaceutical industry as a solubilizing agent to enhance the solubility and bioavailability of poorly water-soluble drugs. It forms inclusion complexes with hydrophobic drug molecules, allowing them to dissolve more effectively in aqueous solutions. This property is particularly valuable in the formulation of oral and injectable medications, improving their efficacy and stability.
In the food and cosmetics industries, it acts as a stabilizer and carrier for flavors, fragrances, and active ingredients, ensuring their controlled release and prolonged shelf life. Additionally, it is employed in biotechnology and research as a tool for protein stabilization and cholesterol extraction from cell membranes, aiding in the study of membrane dynamics and protein-lipid interactions. Its biocompatibility and non-toxic nature make it a versatile excipient in various applications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Specific Rotation (20°C, 1 H2O) | 120-135 |
| Water (Karl Fischer) | 0-7.5% |
| Appearance | White to off-white powder |
| Infrared Spectrum | Conforms to Structure |
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