Retinoic acid is widely used in dermatology for treating acne and other skin disorders. It helps normalize skin cell turnover and prevents the formation of comedones, making it effective in managing both inflammatory and non-inflammatory acne. It is also used to reduce the appearance of fine lines, wrinkles, and hyperpigmentation, promoting smoother and more even-toned skin.

In skincare products, retinoic acid stimulates collagen production, improving skin elasticity and texture over time. It is commonly prescribed for photoaging caused by long-term sun exposure.

Beyond dermatology, retinoic acid plays a role in cancer treatment, particularly in acute promyelocytic leukemia (APL), where it induces differentiation of abnormal white blood cells into mature forms, leading to remission in many patients.

Its ability to regulate cell growth and differentiation also makes it valuable in research, especially in studies related to development, stem cells, and gene expression.