4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl

10mM in DMSO

Reagent Code: #216305
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CAS Number 57852-57-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 533.95 g/mol
Formula C₂₆H₂₇NO₉·HCl
badge Registry Numbers
MDL Number MFCD00866457
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in cancer research as an anthracycline antibiotic with antitumor activity. It functions by intercalating into DNA and inhibiting topoisomerase II, leading to DNA damage and apoptosis in cancer cells. Studied for its potential in treating various malignancies, particularly leukemia and solid tumors. Due to structural similarity to daunorubicin, it serves as a metabolite and analog in pharmacokinetic and structure-activity relationship studies. Also investigated for reduced cardiotoxicity compared to other anthracyclines, making it a candidate for developing safer chemotherapy agents.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,850.00

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