D-Glucuronic acid plays a key role in the body's detoxification processes, primarily in the liver, where it conjugates with toxins, drugs, and bilirubin to make them more water-soluble for excretion in bile or urine. This conjugation process, known as glucuronidation, is a major phase II metabolic pathway for many pharmaceuticals, including morphine, diazepam, and acetaminophen. It is also a structural component in glycosaminoglycans such as hyaluronic acid and chondroitin sulfate, which are essential for connective tissue, joint lubrication, and skin elasticity. Due to this, D-glucuronic acid is involved in tissue repair and is used in some biomedical and cosmetic applications targeting skin health and wound healing. In industrial applications, it serves as a precursor for the synthesis of vitamin C (ascorbic acid) through microbial fermentation processes. Additionally, it is used in the development of biodegradable polymers and drug delivery systems due to its biocompatibility and natural abundance.