2-Aminopurine
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98%
product.physical_n_chem_properties - string(0) ""
science Other reagents with same CAS 452-06-2
blur_circular Chemical Specifications
description Product Description
Used as a fluorescent probe in biochemical studies to monitor DNA and RNA structure and dynamics due to its sensitivity to base pairing and stacking environments. Commonly incorporated into oligonucleotides to study hybridization, mismatches, and conformational changes through changes in fluorescence intensity. Also applied in enzyme assays involving nucleic acid metabolism, such as polymerase and helicase activity, where it helps track real-time nucleotide incorporation and unwinding processes. Its ability to mimic adenine allows it to serve as a non-perturbing label in nucleic acid systems.
Additionally, 2-Aminopurine is used in DNA mutagenesis studies, as it can induce errors in DNA replication by ambiguously pairing with thymine or cytosine, helping researchers understand mechanisms of mutation and DNA repair.
It has also been investigated for potential applications in developing antiviral drugs or bioactive compounds, though these remain in the research stage.
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