Used to treat serious bacterial infections, particularly those caused by multidrug-resistant Gram-negative bacteria. Effective in managing infections in the respiratory tract, urinary tract, skin, bones, joints, and bloodstream. Commonly used in hospital settings for severe infections when other antibiotics fail. Often part of combination therapy for treating tuberculosis and infections in immunocompromised patients. Also used in surgical prophylaxis and in managing infections in burn patients. Due to its potency, it is typically reserved for cases where less toxic antibiotics are ineffective.