Piperine is widely used in the food industry as a natural flavor enhancer, particularly in spicy dishes, due to its pungent and slightly bitter taste. It is a key component in black pepper, contributing to its characteristic aroma and flavor profile. In the pharmaceutical sector, piperine is utilized as a bioenhancer, improving the absorption and efficacy of various drugs and nutrients, such as curcumin, by inhibiting certain metabolic enzymes. Additionally, it is incorporated into dietary supplements for its potential antioxidant, anti-inflammatory, and metabolism-boosting properties. In traditional medicine, piperine is employed for its therapeutic benefits, including aiding digestion and relieving discomfort. Its applications also extend to the cosmetic industry, where it is used in formulations for its potential skin-enhancing and anti-aging effects.