Eritadenine is primarily studied for its cholesterol-lowering properties. It functions by interfering with the metabolism of methionine and affecting the S-adenosylmethionine (SAMe) cycle, which in turn enhances the conversion of cholesterol into bile acids, promoting its excretion from the body. This mechanism makes eritadenine a compound of interest in dietary supplements and functional foods aimed at supporting cardiovascular health.

It is naturally found in mushrooms, especially shiitake (Lentinula edodes), and contributes to the health benefits associated with mushroom consumption. Due to its natural origin and biological activity, eritadenine is also being explored for use in nutraceuticals and as a lead compound in developing agents for managing hypercholesterolemia. Research continues to evaluate its bioavailability, long-term efficacy, and potential integration into therapeutic regimens for lipid management.