Coniferin is primarily involved in the biosynthesis of lignin, a key structural component in the cell walls of plants, especially in wood and bark. It serves as a monomeric precursor in the formation of guaiacyl units found in lignin polymers, playing a critical role in plant growth and mechanical strength. Due to its natural origin and role in lignin formation, coniferin has attracted interest in sustainable materials and green chemistry applications. It is studied for its potential in bio-based polymer development and as a starting material for synthesizing natural aromatic compounds used in fragrances and pharmaceuticals. Additionally, coniferin exhibits antioxidant properties, making it a candidate for use in cosmetic and skincare formulations aimed at reducing oxidative stress and protecting skin from environmental damage. Research also explores its metabolic derivatives for anti-inflammatory and neuroprotective effects in medicinal applications.