Used as a key intermediate in medicinal chemistry for the synthesis of bioactive molecules, particularly in the development of pharmaceuticals. Its strained bicyclic structure enables efficient exploration of novel chemical space in drug design, especially in creating analogs with improved metabolic stability and binding affinity. Commonly employed in fragment-based drug discovery due to its ability to present functional groups in a three-dimensional orientation. Frequently utilized in the preparation of BOC-protected amine derivatives for further coupling reactions, making it valuable in the construction of complex amine-containing compounds. Also applied in the synthesis of covalent inhibitors and PROTACs, where precise linker geometry is critical.