2-Carboxy-4-fluorophenylboronic acid is widely utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is essential for forming carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. The compound’s boronic acid group acts as a key intermediate, enabling the coupling of aryl halides with aryl boronic acids to create complex organic molecules. Its fluorophenyl moiety can enhance the stability and reactivity of the resulting products, making it useful in drug discovery and development. Additionally, its carboxylic acid group allows for further functionalization, expanding its applications in designing bioactive compounds or polymers. This chemical is also employed in the development of sensors and probes, particularly in detecting saccharides or other biologically relevant molecules, due to its ability to form reversible covalent bonds with diols.