(3,5-Difluoro-2-nitrophenyl)boronic acid is primarily used in organic synthesis as a building block for creating more complex molecules. It is particularly valuable in Suzuki-Miyaura cross-coupling reactions, where it acts as a boronic acid partner to form carbon-carbon bonds. This reaction is widely employed in the pharmaceutical industry to synthesize drug candidates and bioactive compounds. Additionally, its unique structure, featuring both nitro and fluoro substituents, makes it useful in the development of materials with specific electronic or optical properties. It also finds applications in the preparation of sensors and probes due to its ability to interact with various analytes.