Potassium trifluoro(2-methylbenzyl)borate is used as a reagent in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It serves as a stable source of the 2-methylbenzyl nucleophile, enabling the efficient introduction of this arylalkyl group into pharmaceuticals, agrochemicals, and advanced materials. Its air and water stability allows for cross-coupling reactions under mild conditions, enhancing selectivity and yield in the synthesis of complex fluorinated or non-fluorinated compounds. Commonly applied in medicinal chemistry for developing drug candidates with improved metabolic profiles.