4,4,5,5-Tetramethyl-2-(5-nitro-2-(trifluoromethoxy)phenyl)-1,3,2-dioxaborolane
97%
Reagent
Code: #131696
CAS Number
2236064-16-5
blur_circular Chemical Specifications
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Molecular Information
Weight
333.07 g/mol
Formula
C₁₃H₁₅BF₃NO₅
thermostat
Physical Properties
Boiling Point
376.5±42.0 °C(Predicted)
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Storage & Handling
Density
1.30±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Particularly valuable in pharmaceutical and agrochemical industries for constructing biaryl systems where one partner contains electron-withdrawing or fluorinated substituents. The presence of the nitro and trifluoromethoxy groups enhances reactivity and influences regioselectivity in coupling processes. Its stability and reactivity profile make it suitable for late-stage functionalization in drug discovery and development of functional materials.
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