3-(Bromomethyl)benzene-1-sulfonyl fluoride
95%
Reagent
Code: #153539
CAS Number
79686-36-5
blur_circular Chemical Specifications
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Molecular Information
Weight
253.09 g/mol
Formula
C₇H₆BrFO₂S
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Registry Numbers
MDL Number
MFCD31445396
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a highly reactive electrophilic reagent in organic synthesis, particularly in the development of covalent inhibitors for biological targets. Its sulfonyl fluoride group reacts selectively with nucleophilic amino acid residues such as serine, threonine, and lysine in enzymes, making it valuable in chemical biology for activity-based protein profiling (ABPP). The bromomethyl group allows for further functionalization via nucleophilic substitution, enabling conjugation to tags, probes, or solid supports. It is also employed in the synthesis of sulfonyl fluoride-containing compounds for use in medicinal chemistry and agrochemical research due to their stability and unique reactivity.
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