N-(2-Aminoethyl)maleimide Hydrochloride is widely used in biochemical and bioconjugation applications due to its reactivity with thiol groups. It is commonly employed to modify proteins, peptides, and other biomolecules by selectively attaching to cysteine residues, enabling the study of protein structure, function, and interactions. This compound is also utilized in the preparation of antibody-drug conjugates (ADCs) for targeted cancer therapies, where it links cytotoxic agents to antibodies. Additionally, it serves as a crosslinking agent in the development of biosensors and diagnostic tools, facilitating the immobilization of biomolecules on surfaces for analytical purposes. Its role in labeling and tracking biomolecules in research further underscores its importance in molecular biology and biochemistry.