15(S)-HEDE is primarily used in research settings to study its role in inflammatory and cardiovascular processes. It is a metabolite of arachidonic acid and is known to influence pathways related to inflammation and vascular function. Researchers utilize it to investigate its effects on endothelial cells, which line blood vessels, to understand its potential impact on conditions like atherosclerosis and hypertension. Additionally, it is studied for its interactions with enzymes and receptors involved in the regulation of blood pressure and inflammation, making it a valuable tool in biomedical research aimed at developing therapeutic strategies for cardiovascular diseases.