(±)15-HEPE is primarily studied for its potential therapeutic applications in inflammation and immune response modulation. It is known to act as a bioactive lipid mediator, influencing pathways that regulate inflammatory processes. Research suggests it may play a role in mitigating chronic inflammatory conditions, such as arthritis, by interfering with the production of pro-inflammatory molecules. Additionally, (±)15-HEPE has been explored for its potential benefits in cardiovascular health, as it may help reduce the risk of atherosclerosis by promoting anti-inflammatory and anti-thrombotic effects. Its application in skincare is also being investigated, with studies indicating it could help manage inflammatory skin disorders like eczema or psoriasis. Further research is ongoing to fully understand its mechanisms and potential clinical uses.