(±)11(12)-EET is a biologically active epoxide metabolite of arachidonic acid, generated through the cytochrome P450 monooxygenase pathway. It is primarily studied for its role in biological systems, particularly in cardiovascular and inflammatory processes.

As a signaling molecule in the endothelium, it influences blood vessel dilation and promotes vasodilation, which can help regulate blood pressure. Additionally, it has been shown to possess anti-inflammatory properties, making it a potential therapeutic target for conditions like atherosclerosis and hypertension.

Researchers are also exploring its role in cellular protection and its potential to mitigate tissue damage in ischemic conditions, such as heart attacks or strokes. Its involvement in lipid metabolism further extends its relevance in metabolic and cardiovascular research.

Emerging studies highlight its renoprotective effects, with potential applications in diabetes and chronic kidney disease. In cancer biology, (±)11(12)-EET may influence tumor growth and metastasis, positioning it as a target for novel anti-cancer therapies.