Sodium taurohyodeoxycholate hydrate is primarily used in biochemical and pharmaceutical research as a bile salt surfactant. It plays a critical role in solubilizing lipids and membrane proteins, making it valuable for studying cell membranes and protein interactions. In drug delivery systems, it enhances the absorption of poorly soluble drugs by improving their solubility in aqueous environments. Additionally, it is utilized in cell culture applications to mimic physiological conditions, particularly in studies involving liver and intestinal cells. Its ability to form micelles also makes it useful in chromatography for separating and analyzing complex biological samples.