Used in pharmaceutical research as a rigid, lipophilic building block to improve metabolic stability and binding affinity in drug candidates. Its unique strained structure serves as a bioisostere for phenyl or tert-butyl groups, enabling better optimization of pharmacokinetic properties. Commonly applied in the development of CNS drugs and protease inhibitors due to its ability to enhance membrane permeability and resistance to oxidative metabolism. Also employed in agrochemicals for designing novel active ingredients with improved environmental stability.